Publications


  • P. Ayata, J. M. Crowley, M. F. Challman, V. Sahasrabuddhe, M. Gratuze, S. Werneburg, D. Ribeiro, E. C. Hays, V. Durán-Laforet, T. E. Faust, P. Hwang, F. Mendes Lopes, C. Nikopoulou, S. Buchholz, R. E. Murphy, T. Mei, A. A. Pimenova, C. Romero-Molina, F. Garretti, T. A. Patel, et al. Lymphoid Gene Expression Supports Neuroprotective Microglia Function. Nature, 2025. DOI: https://doi.org/10.1038/s41586-025-09662-z.

    Colorful depiction of neurons, with a central blue area surrounded by green and yellow structures on a dark background.

  • T. E. Faust, Y.-H. Lee, C. D. O’Connor, M. A. Boyle, G. Gunner, V. Durán-Laforet, L. L. Ferrari, R. E. Murphy, A. Badimon, K. Sakers, C. Eroglu, P. Ayata, A. Schaefer, D. P. Schafer. Microglia-Astrocyte Crosstalk Regulates Synapse Remodeling via Wnt Signaling. Cell, 2025. DOI: https://doi.org/10.1016/j.cell.2025.08.023.


  • A. Flury, L. Aljayousi, H.-J. Park, M. Khakpour, J. Mechler, S. Aziz, J. D. McGrath, P. Deme, C. Sandberg, F. González Ibáñez, O. Braniff, T. Ngo, S. Smith, M. Velez, D. M. Ramirez, D. Avnon-Klein, J. W. Murray, J. Liu, M. Parent, S. Mingote, et al. A Neurodegenerative Cellular Stress Response Linked to Dark Microglia and Toxic Lipid Secretion. Neuron, 2025, 113 (4), 554-571.e14. DOI: https://doi.org/10.1016/j.neuron.2024.11.018.

    A photo of an electron micrographs

  • A. Flury, L. Aljayousi, S. Aziz, H.-J. Park, M. Khakpour, C. Sandberg, F. G. Ibáñez, O. Braniff, P. Deme, J. D. McGrath, T. Ngo, J. Mechler, D. M. Ramirez, D. Avnon-Klein, J. W. Murray, J. Liu, N. J. Haughey, S. Werneburg, M.-È. Tremblay, P. Ayata. Integrated Stress Response Associated with Dark Microglia Promotes Microglial Lipogenesis and Contributes to Neurodegeneration. preprint. bioRxiv 2024.03.04.582965; doi: https://doi.org/10.1101/2024.03.04.582965


  • W. T. Ralvenius, A. E. Mungenast, H. Woolf, M. M. Huston, T. Z. Gillingham, S. K. Godin, J. Penney, H. P. Cam, F. Gao, C. G. Fernandez, B. Czako, Y. Lightfoot, W. J. Ray, A. Beckmann, A. M. Goate, E. Marcora, C. Romero-Molina, P. Ayata, A. Schaefer, E. Gjoneska, et al. A Novel Molecular Class That Recruits HDAC/MECP2 Complexes to PU.1 Motifs Reduces Neuroinflammation. Journal of Experimental Medicine, 2023, 220 (11), e20222105. DOI: https://doi.org/10.1084/jem.20222105.

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