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P. Ayata, A. Badimon, H. J. Strasburger, M. K. Duff, S. E. Montgomery, Y.-H. E. Loh, A. Ebert, A. A. Pimenova, B. R. Ramirez, A. T. Chan, J. M. Sullivan, I. Purushothaman, J. R. Scarpa, A. M. Goate, M. Busslinger, L. Shen, B. Losic, A. Schaefer. Epigenetic Regulation of Brain Region-Specific Microglia Clearance Activity. Nat Neurosci, 2018, 21 (8), 1049–1060. DOI: https://doi.org/10.1038/s41593-018-0192-3.
This study revealed answers to the existence, regulation, and biological significance of microglia regional specification. It introduced significant methodological advancement in the field allowing bona fide microglial molecular signature profiling.
